منابع مشابه
Flow Cytometry
Flow cytometry is a technology that has impacted both basic cell biology and clinical medicine in a very significant manner. The essential principle of flow cytometry is that single particles suspended within a stream of liquid are interrogated individually in a very short time as they pass through a light source focused at a very small region. The optical signals generated are mostly spectral ...
متن کاملFlow Cytometry
Because it has been difficult to identify and separate malignant cells in human lymphoid malignancies, we have developed a flow cytometry-based fluorescent in situ hybridization (FISH) technique using immunoglobulin (Ig) heavy chain variable region (V H) gene probes. After obtaining the specific V H gene sequence expressed by the multiple myeloma IM-9 cell line and the malignant cells in five m...
متن کاملAn Introduction to Automated Flow Cytometry Gating Tools and Their Implementation
Current flow cytometry (FCM) reagents and instrumentation allow for the measurement of an unprecedented number of parameters for any given cell within a homogenous or heterogeneous population. While this provides a great deal of power for hypothesis testing, it also generates a vast amount of data, which is typically analyzed manually through a processing called "gating." For large experiments,...
متن کاملUsing flow cytometry to quantify microbial heterogeneity.
Flow cytometry is a powerful technique for the study of single cells, and thus it is of particular utility in the study of heterogeneity in microbial populations. This review seeks to highlight the role of flow cytometric analyses in studies of microbial heterogeneity, drawing wherever possible on recently published research articles. Whilst microbial heterogeneity is well documented in both na...
متن کاملApplications of Flow Cytometry to Clinical Microbiology
Microbiology in general and clinical microbiology in particular have witnessed important changes during the last few years. Traditional methods of bacteriology and mycology require the isolation of the organism prior to identification and other possible testing. In most cases, culture results are available in 48 to 72 h. Virus isolation in cell cultures and detection of specific antibodies have...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1992
ISSN: 0021-9746
DOI: 10.1136/jcp.45.3.275-d